This course offers an immersive experience into the world of DNA, genes, and genomes in eukaryotic organisms.  In addition to getting a grasp of the foundational biology, we will become familiar with the computational algorithms and methodologies used to analyze and mine the ever-increasing data generated from whole-genome sequencing, high-throughput proteomic analyses, and our improved understanding of evolutionary relationships between organisms based on their molecular fingerprints.  For the project portion of the course, all students will utilize public genomic databases and software to contribute to a multi-institute on-going analysis and annotation of understudied regions of the Drosophila genome.  This project work makes students eligible for future co-author status on emerging publications by the Genomics Education Partnership consortium.