Human works alter the composition of natural worlds and the works of nature impinge upon social worlds. Yet so many of our inherited modes of thinking and acting are premised on a hard and fast distinction between Culture and Nature, the human and non-human, the subject and the object. In this seminar, we will explore a growing body of scholarship that privileges moments of entanglement over any hierarchy of life. Looking at the inhabited landscapes of asthma, labor, difference, and planetary crisis or at the constitutive relations human communities have developed with sugar, fruit flies, mushrooms, and microbes, we will familiarize ourselves with the theoretical placement and analytical methods at work in these entangled worlds. Projects in the seminar will explore the genres of criticism, scales of analysis, and practices of intervention that might now be needed to reflect on and live with these entangled worlds.